- Early Stage Researcher, Newcastle University, UK
- WP2: ER stress, intracellular signalling cascades and biomechanical consequences
- Secondment to MCRI, August-December 2019
Helen is a PhD student, supervised by Prof Michael Briggs at Newcastle University. Her research project aims to investigate the effects of endoplasmic reticulum stress, as it frequently occurs in skeletal dysplasia, on epigenetic factors such as DNA methylation. These studies are based on mouse models of chondrodysplasia as well as cell lines.
During her RUBICON secondment in Prof John Bateman’s and Dr Shireen Lamande’s group, she was trained in the culture and differentiation of human induced pluripotent stem cells (hiPSCs) and their use as in vitro model system. She was also trained in various methods involving histology and molecular biology to analyse the iPSC cultures.